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| Description | HCV residues 131–140, an HLA-restricted CD8+ T epitope; used for HCV-specific T-cell responses, viral clearance and therapeutic vaccines. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| HCV Peptide (131-140) (hepatitis C virus core protein 131-140 decapeptide) | HCV Core (131-140), ADLMGYIPLV, H-Ala-Asp-Leu-Met-Gly-Tyr-Ile-Pro-Leu-Val-OH | HCV core protein epitope, HLA-A2-restricted CTL epitope, immunodominant epitope, hepatitis C vaccine / cellular immunity, Met-containing (antioxidation), hydrophobic peptide (DMSO-assisted), Tyr-containing (light-protected) | H-Ala-Asp-Leu-Met-Gly-Tyr-Ile-Pro-Leu-Val-OH (ADLMGYIPLV, linear 10-mer, free N-terminal amino group and free C-terminal carboxyl; contains 1 Met and 1 Tyr, no Cys) | C51H82N10O14S | 1090.57 | 1091.33 | Not specified (typically TFA salt for synthetic peptides; per Certificate of Analysis) | 10 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-HCV131-01 | white to off-white powder | Store desiccated and sealed below -20°C, protected from light; stable as powder; reconstituted aliquots protected from light can be stored long-term at -80°C | Carry or use short-term at 4°C sealed, desiccated and protected from light; use within 2 weeks; after reconstitution, aliquot and store at -20°C/-80°C, avoid repeated freeze-thaw | ~70% hydrophobic residues (Leu x2, Val, Ile, Pro, Ala, etc.); a strongly hydrophobic viral epitope with poor aqueous solubility-first dissolve in DMSO, then dilute with PBS/buffer; contains 1 Met susceptible to oxidation, avoid oxidizing agents and prefer deoxygenated/inert-gas storage; contains 1 Tyr, keep protected from light; no Cys, so no dimer/disulfide concern | Stable as powder when desiccated, light-protected and sealed at -20°C; protect from moisture; aliquot promptly after opening and keep in a desiccator |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-HCV131-01 | The 131-140 decapeptide ADLMGYIPLV of the hepatitis C virus core protein (HCV Core); an HLA-A2-restricted immunodominant cytotoxic T lymphocyte (CTL) epitope, used in HCV cellular immunity and vaccine epitope research. | This peptide corresponds to residues 131-140 (ADLMGYIPLV) of the hepatitis C virus core (Core) protein. Chang KM et al. (J Clin Invest, 1997) described it as an HLA-A2 (HLA-A*0201)-restricted immunodominant CTL epitope, one of the classical target epitopes recognized by peripheral-blood CD8+ T cells of HCV-infected individuals. It is used for epitope-specific CD8+ T-cell response assays, immunization of HLA-A2 transgenic mice, screening of candidate vaccine epitopes, and studies of HCV cellular immunity. Order by the sequence ADLMGYIPLV and CAS 160926-86-3. | HCV hepatitis, CD8 T cell epitope mapping, HLA-A2-restricted cellular immunity, HCV vaccine epitope screening, virus-specific T-cell recognition | HLA-A2 (HLA-A*0201) MHC class I molecules (presentation); HCV Core-specific CD8+ cytotoxic T cell receptors (TCR) |
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