CAS 92000-72-1 Influenzahemagglutinin(HA)epitope

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CAS 92000-72-1 Influenzahemagglutinin(HA)epitope
Details
Influenza hemagglutinin epitope peptide;
Category: Influenza surface antigen epitope / HA neutralizing & T peptide.
Peptide Purity (HPLC) ≥95%
CAS No. 92000-72-1
Structure Linear HA-derived antigen epitope
Solubility Water/PBS; minor cosolvent
Storage Powder, −20°C, dry, light-protected
Category
Epitope Peptides
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Description

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Description An antigenic epitope from influenza HA, a key region for neutralizing antibodies and T-cell recognition; used for subunit-vaccine epitope selection, drift monitoring and serology.

 

Product Basic Information Table

 

Product Standard English Name Product Abbreviation / Alias Function Tags (comma-separated) Core Structure Molecular Formula Exact Mass (Da) Average MW (Da) Salt Form Length (aa)
Influenza haemagglutinin (HA) epitope HA tag peptide, HA111-119, 12CA5 epitope, CYPYDVPDYA, HA epitope tag [CAS 92000-72-1] Influenza HA tag epitope, antibody detection, protein tag, antibody production CYPYDVPDYA (H-Cys-Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala-OH, 10-aa linear; N-terminal Cys for conjugation to carrier proteins such as KLH/BSA) C56H72N10O18S 1204.47 1205.30 Free acid 10

 

Physicochemical Solubility & Storage Parameters

 

Product Code Appearance Long-term Storage Short-term Storage Solution Stability Solid Powder Stability
PEP-HAEP-01 powder, white to off-white Store desiccated and sealed below -20°C, protected from light; powder stable for 2-3 years; reconstituted aliquots can be stored at -80°C for ~1 year Store sealed and desiccated at 4°C, use within 2-4 weeks; after reconstitution, aliquot and store frozen at -20°C, avoid repeated freeze-thaw Contains 1 Cys (oxidation-sensitive; deoxygenate / inert-gas blanket to avoid dimerization) and 2 Tyr (light-sensitive; protect from light); net charge -2 (2 Asp). Hydrophobic residues ~40%, moderate water solubility: first dissolve in DMSO or a small volume of dilute buffer (PBS pH 7-8), then sonicate/vortex until fully dissolved powder stable for 2-3 years at -20°C when desiccated and sealed; protect from moisture and light; after opening, aliquot promptly and keep in a desiccator to prevent Cys oxidation from moisture uptake

 

Functional Description

 

Product Code Frontend Short Summary Detailed Biological Function Description Applicable Research Areas (comma-separated) Targets / Pathways
PEP-HAEP-01 Classic immunodominant epitope YPYDVPDYA from influenza hemagglutinin (HA residues 111-119), extended with an N-terminal Cys (CYPYDVPDYA) for conjugation to KLH etc.; widely used for anti-HA antibody production and detection/identification of HA-tagged fusion proteins. This sequence corresponds to residues 111-119 (YPYDVPDYA) of influenza A virus hemagglutinin (HA, H3 strain), the classic immunodominant epitope recognized by monoclonal antibody 12CA5 and one of the most widely used protein epitope tags. The N-terminal cysteine allows thiol-mediated conjugation to carrier proteins such as KLH or BSA for immunizing mice/rabbits to generate anti-HA polyclonal or monoclonal antibodies. The peptide also serves as the HA tag for detection of fusion proteins by Western blot, immunoprecipitation and immunofluorescence. Contains 1 Cys and 2 Tyr; handle under oxidant-free, light-protected conditions. Immunology research, antibody production, protein tag detection, fusion protein identification, vaccine research Recognized by anti-HA mAb 12CA5; HA-tagged fusion proteins; conjugatable to KLH/BSA carriers

 

 

 

 

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