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| Description | The classical human encephalitogenic region of MBP that actively/passively induces experimental autoimmune encephalomyelitis; a core tool for MS pathogenesis, immunomodulation and tolerance therapy. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Experimental Allergic Encephalitogenic Peptide (Human) | Experimental allergic encephalitogenic peptide (human); FSWGAEGQR; human MBP 114-122 (suppliers: 115-123); EAE encephalitogenic peptide; CAS 29705-92-8 | Experimental allergic encephalomyelitis (EAE),Multiple sclerosis (MS),Myelin autoimmunity,Demyelinating disease models | H-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH; a classic encephalitogenic (EAE) epitope from human myelin basic protein (MBP) residues 114-122; note: suppliers label it MBP (115-123), an isoform-numbering difference-sequence FSWGAEGQR is identical; linear peptide with free N-terminal amine / free C-terminal carboxyl; contains 1 Trp-protect from light. | C46H64N14O14 | 1036.47 | 1037.10 | free powder (TFA / acetate available on request) | 9 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-EAE-01 | White to off-white powder (may appear pale yellow due to Trp). | -20°C, dry and sealed; contains Trp-keep fully light-protected (amber foil/vial); avoid repeated freeze-thaw. | 2-8°C, light-protected; use within 1 week. | Soluble in water/PBS; as an MBP-type peptide watch for aggregation-reconstitute gently, avoid high-concentration standing, prepare fresh; contains 1 Arg-a small amount of dilute acetic acid may aid solubility; contains Trp-protect from light. | powder is stable ~1-2 years at -20°C dry and light-protected. |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-EAE-01 | Human MBP-derived encephalitogenic 9-mer FSWGAEGQR (114-122) for EAE/multiple sclerosis autoimmunity research. | This 9-mer is a classic encephalitogenic EAE epitope of human MBP that induces experimental allergic encephalomyelitis in guinea pigs and other animals; a classic tool peptide for studying myelin-specific autoimmunity, demyelinating disease and the immunopathology of multiple sclerosis (MS). Contains Trp-protect from light. | Experimental allergic encephalomyelitis (EAE),Multiple sclerosis (MS),Myelin autoimmunity,Demyelinating disease models | MBP-specific autoreactive T cells; EAE model |
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