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| Description | The hydrophobic 20-mer ELAAWCRWGFLLALLPPGIAG, TFA salt, for long-peptide epitope mapping, MHC presentation and T-cell assays; requires DMSO/detergent cosolvent. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| ELAAWCRWGFLLALLPPGIAG (P5), TFA salt (rat HER2/neu residues 5-25 CTL epitope peptide) | P5 peptide, ELAAWCRWGFLLALLPPGIAG TFA, rat HER2/neu P5 (aa 5-25) | T-cell epitope, CTL epitope, MHC class I, cancer vaccine, HER2, dendritic cell vaccine, TFA salt | ELAAWCRWGFLLALLPPGIAG (H-Glu-Leu-Ala-Ala-Trp-Cys-Arg-Trp-Gly-Phe-Leu-Leu-Ala-Leu-Leu-Pro-Pro-Gly-Ile-Ala-Gly-OH, linear 21-mer, TFA salt) | C109H164N26O24S | 2253.21 | 2254.72 | TFA salt (trifluoroacetate counterion, per TargetMol) | 21 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-HER2P5T-01 | white to off-white (TFA salt, TargetMol, purity ≥95% HPLC) | Store frozen below -20 C, protected from light, dry and tightly sealed (TFA salt is hygroscopic; keep tightly sealed) | Store at 4 C sealed, dry and light-protected, use within 2-4 weeks; aliquot immediately after reconstitution and store at -20 C, avoid repeated freeze-thaw | Highly hydrophobic (~57% hydrophobic), poorly water-soluble: dissolve first in DMSO or acetonitrile as a stock (e.g. 5-10 mg/ml in DMSO), then dilute with water/PBS or buffer containing 0.1% Tween-20; sonication may help; contains 1 Cys (oxidation-prone, guard against dimerization) and 2 Trp (light-sensitive); protect from light, deoxygenate and use promptly after reconstitution | powder stable long-term at -20 C when dry, light-protected and sealed; keep moisture- and light-protected; Cys is oxidation-sensitive (can form disulfide dimers), avoid prolonged air exposure |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Receptors |
| PEP-HER2P5T-01 | The TFA-salt form of rat HER2/neu P5 peptide (aa 5-25), a highly hydrophobic CTL epitope that induces cytotoxic T-lymphocyte responses in HER2-positive tumor-bearing mice. | ELAAWCRWGFLLALLPPGIAG (P5) is a highly hydrophobic 21-mer CTL epitope spanning residues 5-25 of rat HER2/neu. P5-pulsed dendritic cells act as a preventive cancer vaccine, eliciting cytotoxic T-lymphocyte (CTL) responses in HER2-positive tumor-bearing mice. This entry is the trifluoroacetate (TFA) salt formulation, which typically carries no separate CAS number. | Tumor immunology, cancer vaccine, CTL epitope, MHC class I, HER2-targeted therapy, dendritic cell vaccine | MHC class I (CTL recognition; rat HER2/neu P5) |
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