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| Description | An ovalbumin-derived HLA-A0201-binding CD8+ T-cell epitope, a classic model antigen for T-cell immunology; used for antigen presentation, CTL killing, tumor models and vaccine-adjuvant evaluation. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| OVA-A2 Peptide | SAINFEKL (OVA 257-264 variant), OVA-A2, SAINFEKL, OVA (257-264) Variant | Ovalbumin epitope peptide, SIINFEKL analog (APL), H-2Kb antigenic variant, CD8+ T cell research | SAINFEKL (H-Ser-Ala-Ile-Asn-Phe-Glu-Lys-Leu-OH, linear 8-mer) | C42H68N10O13 | 920.50 | 921.06 | Free acid (free base) | 8 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-OVAA2-01 | white to off-white powder (typical form of synthetic epitope peptides; appearance not separately published on this SKU page) | Store frozen below -20°C, protected from light, in a dry and sealed container; stable for 3 years as powder at -20°C (TargetMol); keep away from moisture; shipped on blue ice or at ambient temperature | Store sealed and dry at 4°C, use within 2-4 weeks; after reconstitution, aliquot into single-use portions and freeze below -20°C, avoid repeated freeze-thaw cycles | Good water solubility (homolog SIINFEKL is soluble in water >1 mg/mL); reconstitute in water or acidic buffer, with a small amount of DMSO if needed; solution is stable for 1 year at -80°C (TargetMol); net charge 0, no Cys/Met/Trp/Tyr, no special oxidation or light-sensitivity requirements | powder is stable for 3 years at -20°C (TargetMol); keep moisture-proof, light-protected and sealed; no special structural degradation concern such as N-terminal Glu cyclization |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-OVAA2-01 | SAINFEKL is the I258A altered peptide ligand of the canonical H-2Kb epitope SIINFEKL (OVA 257-264) from chicken ovalbumin; an 8-mer linear peptide for MHC-I antigen presentation and CD8+ T cell recognition studies. | SAINFEKL is derived from chicken ovalbumin (OVA). It is a single-amino-acid substituted analog (altered peptide ligand, APL; Ile258->Ala) of the canonical mouse H-2Kb-restricted CD8+ T cell epitope SIINFEKL (OVA 257-264), and retains antigenicity. Suppliers (TargetMol/MCE) list it as "SAINFEKL, OVA (257-264) Variant" and do not label it as HLA-A2 restricted. As an MHC-I-binding antigenic peptide, it is used in antigen presentation pathways, CD8+ T cell activation, APL cross-reactivity studies, and epitope-peptide vaccine/immunogenicity research. | Vaccine immunology, MHC-I antigen presentation, CD8+ T cell detection, APL analog research, Tetramer staining | MHC-I (presented by H-2Kb); CD8+ T cell receptor (TCR) |
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