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| Description | An antigenic epitope of rotavirus VP7 (residues 31–40), a key region for neutralizing-antibody and T-cell responses; used for subunit-vaccine epitope screening and serodiagnosis. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| Rotavirus VP7 (31-40) Peptide | Rotavirus VP7 31-40, SA11 VP7 CTL epitope, DYIIYRFLLI, CAS 152687-39-3 | Rotavirus epitope peptide, H-2Kb-restricted, CD8+ CTL epitope, Immunodominant, Serotype-specific, T cell assay | DYIIYRFLLI (H-Asp-Tyr-Ile-Ile-Tyr-Arg-Phe-Leu-Leu-Ile-OH, linear 10-mer, free N/C termini) | C67H101N13O15 | 1327.75 | 1328.62 | TFA salt (typical) | 10 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-VP7-01 | White to off-white powder | Store frozen below -20°C, protected from light, sealed and dry; avoid repeated freeze-thaw cycles | Store sealed and dry at 4°C, use within 2-4 weeks; aliquot and store reconstituted solution at -20°C | Hydrophobic peptide (~60% hydrophobic residues, enriched in Ile/Tyr/Phe/Leu; net charge 0): prepare a stock solution in DMSO first, then dilute with water or buffer to working concentration. Contains 2 Tyr residues - strictly protect from light during handling and storage to prevent tyrosine photo-oxidation | powder is stable sealed, dry and light-protected at -20°C; protect from moisture and light |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-VP7-01 | Synthetic peptide of rotavirus group A (simian SA11 strain) outer capsid glycoprotein VP7 residues 31-40; an H-2Kb-restricted, serotype-specific immunodominant CD8+ CTL epitope for rotavirus cellular immunity and vaccine research | This is a synthetic peptide corresponding to residues 31-40 of VP7, the major outer capsid glycoprotein defining G serotypes of group A rotavirus (representative strain: simian SA11). It was mapped by synthetic peptides in SA11-infected C57BL/6 (H-2b) mice as an H-2Kb-restricted immunodominant CD8+/CTL epitope, located within the N-terminal first hydrophobic domain (H1) of VP7, and is serotype-specific (no cross-reactivity). It is a classical target epitope for rotavirus-specific cellular immunity studies, used for CTL epitope mapping, peptide-MHC binding and T cell recognition studies, and rotavirus vaccine / pathogenesis research (PMID 9152424; PMID 10329553). | Viral immunology, Rotavirus infection, CD8+ T cell detection, CTL epitope mapping, Vaccine development | H-2Kb (MHC-I presentation); T cell receptor (TCR) |
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