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| Description | CMV pp65 (UL83) residues 13–27, a region frequently recognized by CMV-specific CD4+/CD8+ T cells; pp65 is central to post-transplant CMV immune monitoring and vaccines. |
Product Basic Information Table
| Product Standard English Name | Product Abbreviation / Alias | Function Tags (comma-separated) | Core Structure | Molecular Formula | Exact Mass (Da) | Average MW (Da) | Salt Form | Length (aa) |
| CMV pp65 (13-27) (Human Cytomegalovirus UL83 pp65 Matrix Phosphoprotein Residues 13-27 T-cell Epitope Peptide; CAS 357643-84-6) | HCMV pp65 (13-27), SVLGPISGHVLKAVF, CMV pp65 aa13-27, H-Ser-Val-Leu-Gly-Pro-Ile-Ser-Gly-His-Val-Leu-Lys-Ala-Val-Phe-OH, PEP-CMVPP65-01 | Human cytomegalovirus (HCMV), pp65/UL83 matrix phosphoprotein, T-cell epitope, HLA-restricted immune monitoring, CMV vaccine research, ~60% hydrophobic, DMSO-assisted | H-Ser-Val-Leu-Gly-Pro-Ile-Ser-Gly-His-Val-Leu-Lys-Ala-Val-Phe-OH (SVLGPISGHVLKAVF, linear 15-mer, free N-terminal amino / free C-terminal carboxyl); residues 13-27 of the HCMV pp65 65-kDa matrix phosphoprotein encoded by UL83; contains only 1 His, no Cys/Met/Trp/Tyr | C72H118N18O18 | 1522.89 | 1523.84 | Not specified (per COA) | 15 |
Physicochemical Solubility & Storage Parameters
| Product Code | Appearance | Long-term Storage | Short-term Storage | Solution Stability | Solid Powder Stability |
| PEP-CMVPP65-01 | white to off-white | Store frozen below -20°C, dry, sealed and light-protected; powder stable for ~2-3 years; reconstituted aliquots stored at -20°C for ~6 months | Store sealed, dry and light-protected at 4°C, use within 2-4 weeks; after reconstitution aliquot and store at -20°C, avoid repeated freeze-thaw | ~60% hydrophobic residues (Val/Leu/Ile/Ala/Phe), moderate water solubility-reconstitute in sterile water or pH 7.4 PBS; if needed, first dissolve in a small volume of DMSO then dilute with buffer (keep final DMSO <=10%); no Cys/Met/Trp/Tyr, so no special antioxidation/stringent light protection is required-routine light protection suffices | powder stable for ~2-3 years at -20°C when dry, sealed and light-protected; protect from moisture and light; weigh promptly after opening and keep in a desiccator |
Functional Description
| Product Code | Frontend Short Summary | Detailed Biological Function Description | Applicable Research Areas (comma-separated) | Targets / Pathways |
| PEP-CMVPP65-01 | The 15-mer SVLGPISGHVLKAVF from residues 13-27 of the human cytomegalovirus (HCMV) pp65 (UL83) matrix phosphoprotein, a T-cell epitope-region peptide used in HCMV immune-response monitoring, T-cell epitope identification and CMV vaccine research. | The HCMV pp65 protein, encoded by UL83, is the most abundant 65-kDa matrix phosphoprotein in virions and one of the core target antigens of the HCMV-specific T-cell immune response. This product is the 15-mer SVLGPISGHVLKAVF corresponding to residues 13-27 of pp65, a T-cell epitope-region segment in the N-terminal part of the protein. Note that this segment is entirely distinct from the best-known HCMV pp65 immunodominant epitope pp65 495-503 (NLVPMVATV, an HLA-A*0201-restricted CD8+ CTL epitope); order by the sequence SVLGPISGHVLKAVF and CAS 357643-84-6. The peptide is used for monitoring T-cell immune responses after HCMV infection, T-cell epitope identification and typing, candidate-epitope screening for CMV vaccines, and ex vivo antigen-specific T-cell restimulation (proliferation / ELISPOT / intracellular cytokine staining). | Human cytomegalovirus (HCMV), T-cell epitope identification, CMV vaccine research, immune-response monitoring, post-transplant CMV immunity | HCMV pp65 (UL83)-specific T cell receptors (TCR); presented by MHC molecules (restriction per COA/literature) |
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